In lens-induced uveitis, which serious secondary complication can arise?

In lens-induced uveitis, which serious secondary complication can arise?

• A. Glaucoma
• B. Retinal detachment
• C. Macular edema
• D. Optic neuropathy

Answer: (A)

Inflammation from lens-induced uveitis can block aqueous outflow, leading to glaucoma. When lens proteins leak into the anterior chamber, they trigger a robust inflammatory response with cells, fibrin, and debris that can clog the trabecular meshwork. This outflow obstruction raises intraocular pressure. If the pressure stays elevated, it can damage the optic nerve, causing irreversible vision loss, which is why glaucoma is the serious secondary complication associated with lens-induced uveitis. In some cases, inflammatory adhesions (synechiae) can also cause pupillary block or angle closure, further elevating pressure and increasing risk to the optic nerve. While macular edema or optic neuropathy can occur with ocular inflammation, the direct threat to the optic nerve from sustained high IOP makes glaucoma the most critical secondary complication in this scenario.

Inflammation from lens-induced uveitis can block aqueous outflow, leading to glaucoma. When lens proteins leak into the anterior chamber, they trigger a robust inflammatory response with cells, fibrin, and debris that can clog the trabecular meshwork. This outflow obstruction raises intraocular pressure. If the pressure stays elevated, it can damage the optic nerve, causing irreversible vision loss, which is why glaucoma is the serious secondary complication associated with lens-induced uveitis. In some cases, inflammatory adhesions (synechiae) can also cause pupillary block or angle closure, further elevating pressure and increasing risk to the optic nerve. While macular edema or optic neuropathy can occur with ocular inflammation, the direct threat to the optic nerve from sustained high IOP makes glaucoma the most critical secondary complication in this scenario.